{"id":14910,"date":"2026-06-20T12:39:03","date_gmt":"2026-06-20T12:39:03","guid":{"rendered":"https:\/\/dev.iita.org\/news-item\/new-promising-defense-strategy-to-protect-african-maize-from-striga-infestation\/"},"modified":"2026-06-29T21:19:35","modified_gmt":"2026-06-29T21:19:35","slug":"new-promising-defense-strategy-to-protect-african-maize-from-striga-infestation","status":"publish","type":"news-item","link":"https:\/\/iita.org\/fr\/news-item\/new-promising-defense-strategy-to-protect-african-maize-from-striga-infestation\/","title":{"rendered":"New promising defense strategy to protect African maize from Striga infestation"},"content":{"rendered":"<p><a href=\"https:\/\/iita.org\/fr\/\">IITA<\/a>\u2013<a href=\"https:\/\/www.cgiar.org\/\">CGIAR<\/a> scientists have discovered remarkable resistance mechanisms that promise to improve crop protection from <em>Striga<\/em> infestation in Africa and enhance maize production across the continent.<\/p>\n\n<p>In a recent <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0981942823006459\">\u00e9tudier<\/a> researchers found a previously unknown defense strategy based on the accumulation of a secondary metabolite called DIMBOA\u2014a benzoxazinoid\u2014that contributes to blocking <em>Striga <\/em>invasion of the maize root vascular system.<\/p>\n\n<figure id=\"attachment_27022\" aria-describedby=\"caption-attachment-27022\" style=\"width: 820px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-27022\" src=\"https:\/\/iita.org\/wp-content\/uploads\/2026\/06\/Striga-infested-maize-plants-benzoxazinoid-biosynthetic-pathway-and-heatmap-of-target-gene-expression.gif\" alt=\"Striga-infested maize plants, benzoxazinoid biosynthetic pathway, and heatmap of target gene expression.\" width=\"820\" height=\"411\" \/><figcaption id=\"caption-attachment-27022\" class=\"wp-caption-text\">Striga-infested maize plants, benzoxazinoid biosynthetic pathway, and heatmap of target gene expression.<\/figcaption><\/figure>\n\n<p><em>Striga hermonthica\u00a0<\/em>is an invasive parasitic weed entering host plant roots and forming direct vascular connections to the host vascular system, thus withdrawing water and nutrients. Despite its beautiful purple-colored flowers, it is commonly named witchweed to reflect the dramatic effect produced on maize and other major crops, seeming to magically arrest host growth and destroy yield, potentially up to 100%. This nutrient-sucking parasite thrives in\u00a0poor soils with low rainfall conditions and farming systems using minimal or no fertilizer and poor crop management practices.<\/p>\n\n<p>IITA maize breeders have selected a few sources of crop resistance originating from the maize wild relative <em>Zea diploperennis,<\/em> conferring partial resistance after <em>Striga<\/em> germination. In a collaborative effort, IITA molecular biologists, bioinformaticians, and breeders led by Livia Stavolone, Andreas Gisel, Abebe Menkir, and Melaku Gedil have investigated the biological mechanisms exploited by striga-resistant maize plants to defend from the parasite.<\/p>\n\n<p>They demonstrated that the accumulation of DIMBOA, a benzoxazinoid with inhibitory and toxic effects against a wide range of pests, pathogens, and competing plant species, contributes to blocking <em>Striga <\/em>invasion of the maize root vascular system. DIMBOA is produced by specific plant families, particularly grasses, from which it can be extracted and purified, and is therefore commercially available.<\/p>\n\n<p>On the way forward to sustainable and durable <em>Striga<\/em> control in sub-Saharan Africa, this discovery is not only key to breeding and engineering resistant maize plants, it also has potential future applications for direct control in the field.<\/p>\n\n<p>Mature <em>Striga<\/em> plants leave tens of thousands of tiny seeds in the soil, where they can survive for years, ready to infest the maize plant triggered by maize germination. The potency of DIMBOA released from residues of plant cultivations and used for weed control opens future applications to reduce parasitic seed banks in the soil and parasite plant emergence in the field.<\/p>\n\n<em>Contributed by Livia Stavolone<\/em>","protected":false},"excerpt":{"rendered":"<p>IITA-CGIAR scientists have discovered remarkable resistance mechanisms that promise to improve crop protection from Striga infestation in Africa and enhance maize production across the continent.<\/p>","protected":false},"featured_media":14911,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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