{"id":15788,"date":"2026-06-20T12:46:46","date_gmt":"2026-06-20T12:46:46","guid":{"rendered":"https:\/\/dev.iita.org\/news-item\/new-study-offers-first-ever-insight-on-resistance-mechanism-of-a-wild-banana-relative\/"},"modified":"2026-06-29T20:29:54","modified_gmt":"2026-06-29T20:29:54","slug":"new-study-offers-first-ever-insight-on-resistance-mechanism-of-a-wild-banana-relative","status":"publish","type":"news-item","link":"https:\/\/iita.org\/fr\/news-item\/new-study-offers-first-ever-insight-on-resistance-mechanism-of-a-wild-banana-relative\/","title":{"rendered":"New study offers first-ever insight on resistance mechanism of a wild banana relative"},"content":{"rendered":"<h5>R4D Special<\/h5>\n<div id=\"attachment_4821\" class=\"wp-caption alignleft\" style=\"width: 710px\">\n\n<img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-28608\" src=\"https:\/\/iita.org\/wp-content\/uploads\/2026\/06\/New-study-p01-300x150-1.jpeg\" alt=\"\" width=\"710\" height=\"355\" \/>\n<p id=\"caption-attachment-4821\" class=\"wp-caption-text\">A. Musa balbisiana, wild type banana, resistant to\nXanthomonas wilt disease.\nB. Cultivated banana showing Xanthomonas wilt\ndisease symptoms.<\/p>\n\n<\/div>\n&nbsp;\n\n&nbsp;\n\n&nbsp;\n\n&nbsp;\n\nThe Banana Xanthomonas wilt (BXW) disease, caused by a bacterium, Xanthomonas campestris pv. musacearum (Xcm),\u00a0is one of the most devastating diseases endangering the livelihood of millions of farmers in East Africa, the largest banana-producing and -consuming region in Africa.\n\nIt affects all banana cultivars grown in East Africa and only a wild type of banana native to Asia and one of the parents of modern cultivated bananas, Musa balbisiana, has been found to be resistant. However, very little is known about the molecular basis of susceptibility and resistance of banana to the bacterium.\n\nTherefore, to better understand the molecular basis of resistance and susceptibility to the disease, scientists from\u00a0<a href=\"https:\/\/iita.org\/fr\/\">IITA<\/a>-Kenya compared the transcriptome-wide differential gene expression of the BXW-resistant genotype Musa balbisiana and BXW-susceptible genotype Pisang Awak during early bacterial infection. The transcriptome profiling was performed through RNA sequencing in collaboration with\u00a0<a href=\"http:\/\/www.nyu.edu\/\">New York University<\/a>\u00a0(NYU). The differentially expressed transcripts were further mapped to biotic stress pathways to identify genes associated with defense mechanisms. This study suggested activation of both PAMP-triggered basal defense and disease resistance (R) protein-mediated defense in Musa balbisiana as an early response to bacterial infection.\n\nThe results of this research have been published in the international journal Scientific Reports (<a href=\"https:\/\/doi.org\/10.1038\/s41598-019-43421-1\">https:\/\/doi.org\/10.1038\/s41598-019-43421-1<\/a>), and provide insights on the resistance mechanism in Musa balbisiana to the most damaging pathogen Xcm. This study reports the first comparative transcriptome profile of the susceptible and resistant genotype of banana during early bacterial infection.\n\nOne of the scientists leading these efforts\u00a0<a href=\"https:\/\/iita.org\/fr\/iita-staff\/tripathi-leena\/\">Leena Tripathi<\/a>, Principal Scientist in Plant Biotechnology at IITA, Kenya, said \u201cThis new, important knowledge can be used in crop improvement programs to transfer the disease resistance trait from wild type banana to farmer-preferred banana cultivars commonly grown in Africa or editing of genes related to susceptibility and\/or negative regulation of plant immunity.\u201d.\n\nThe BXW disease causes wilting of plants, premature\u00a0ripening\u00a0of the fruits, and eventually, death of the whole plant. Unlike in other banana diseases, which cause incremental losses over years, the impacts of BXW disease are both rapid and extreme. The disease has caused estimated economic losses of about $2-8 billion over the last decade and significant reductions in production have resulted in major price increases.\n\nBanana is the world\u2019s fourth most important food crop and is critical to the food security and income generation of more than\u00a070 million Africans. This study is, therefore, a foundation for further research that would lift millions of smallholder banana farmers out of poverty while helping to alleviate hunger and poverty in Africa through improved production and reducing crop management costs in banana farming. Banana is a major food and income source for smallholder farmers in countries like Burundi, Kenya, Rwanda, Tanzania, Uganda, and eastern parts of the Democratic Republic of Congo.\n\nThis research was supported by the United States Agency for International Development (<a href=\"https:\/\/www.usaid.gov\/\" target=\"_blank\" rel=\"noopener\">USAID<\/a>) and CGIAR Research Program on Roots, Tubers and Bananas (<a href=\"http:\/\/www.rtb.cgiar.org\/\" target=\"_blank\" rel=\"noopener\">CRP-RTB<\/a>).","protected":false},"excerpt":{"rendered":"<p>The Banana Xanthomonas wilt (BXW) disease, caused by a bacterium, Xanthomonas campestris pv.<\/p>","protected":false},"featured_media":15789,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"tags":[1501],"science-area":[],"program":[],"location":[28],"news-type":[],"hub":[62],"crop":[],"impact-areas":[],"item-year":[197],"class_list":["post-15788","news-item","type-news-item","status-publish","has-post-thumbnail","hentry","tag-bxweastern-africaiita-news-no-2488r4d-special","location-kenya","hub-eastern-africa","item-year-197"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - 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